Clinical Safety

Safety & Risks

Plain information about fit, possible effects, monitored care, transportation, group privacy, and when to seek urgent help.

Before Care

What You Need to Know

  • Ketamine-assisted psychotherapy (KAP) uses ketamine in an off-label capacity. While ketamine is FDA-approved as an anesthetic, its use in psychotherapy is considered experimental and is not FDA-approved for psychiatric indications.
  • All participants undergo a clinical screening process to determine appropriateness for ketamine-assisted work. Screening includes medical and psychiatric evaluation.
  • Participants must arrange transportation home after dosing sessions. Do not drive or operate heavy machinery for at least 6 hours after a session or until effects have fully subsided.
  • LuminaThera does not provide emergency or crisis services. If you are in crisis, please call 988 (Suicide & Crisis Lifeline) or go to your nearest emergency room.
  • In group settings, confidentiality depends on all group members. While facilitators maintain professional confidentiality standards, they cannot guarantee the actions of other participants.
  • Therapeutic outcomes vary by individual. KAP is not a cure and does not guarantee specific results. Many participants report meaningful benefit, but individual experiences differ.
  • We do not offer take-home, self-guided ketamine. Experiential sessions are supported and monitored onsite.
The Short Version

Clear information is part of safe care.

Ketamine-assisted psychotherapy can be meaningful for some people, and it carries real medical and psychological risks. Ketamine is FDA-approved as an anesthetic. Its use for mental-health treatment is off-label and considered experimental. Outcomes vary, and no result can be promised.

LuminaThera currently offers sublingual and intramuscular (IM) ketamine within structured care. Every pathway includes medical and psychological screening, informed consent, preparation, supported onsite sessions, and integration. We do not offer take-home, self-guided ketamine.

Read by Topic

The details, organized around the decisions that matter.

Open any section for a fuller explanation. Your individual screening and informed-consent documents control your care.

How does screening work?

Screening is a clinical process, not a pass-or-fail formality. The team considers your goals, current stability, mental-health and medical history, medications and supplements, substance use, prior experiences with ketamine or anesthesia, and the support available before and after a session.

Areas requiring particular attention may include cardiovascular concerns or uncontrolled high blood pressure, active psychosis or untreated mania, pregnancy or breastfeeding, substance-misuse risk, and medication interactions. This is not a complete list. The prescriber may recommend further evaluation, stabilization, medical follow-up, a different treatment, or a higher level of care.

What effects can happen during or after a session?

Ketamine can affect awareness, perception, mood, coordination, judgment, blood pressure, and heart rate. Temporary effects may include altered perception or sense of time, dissociation, dream-like imagery or hallucinations, unusual thoughts, confusion, anxiety, fear, agitation, sadness, euphoria, dizziness, drowsiness, impaired balance or coordination, nausea, vomiting, numbness, increased saliva, blurred or double vision, involuntary eye movement, headache, and increased blood pressure or heart rate. IM administration may cause discomfort at the injection site.

Less common but potentially serious reactions include a marked change in blood pressure or heart rhythm, breathing difficulty, severe agitation or confusion, allergic reaction, loss of consciousness, or another response requiring urgent care. Ketamine also has misuse, abuse, tolerance, and dependence potential. Repeated or high exposure has been associated with bladder or urinary symptoms, liver or biliary injury, and problems with memory or concentration.

What psychological or relational risks should I consider?

An experience may feel peaceful, meaningful, confusing, frightening, or emotionally intense. Difficult memories, grief, fear, shame, or unexpected material may surface. Insight during a session may later feel uncertain or may not lead to lasting change. Symptoms can persist, return, or worsen, and some people do not benefit.

Preparation and integration support safety and meaning-making, but they cannot eliminate uncertainty. Ketamine-assisted psychotherapy is not a cure and does not replace the ongoing care, relationships, habits, and supports recovery may require.

How do monitored sessions reduce risk?

Experiential sessions take place onsite with trained clinical staff. The medical provider determines eligibility, prescribing, route, dose, and medication decisions. The therapy team supports preparation, the session, and integration.

The process includes medical and psychological review, informed consent, pre-session instructions, observation and monitoring appropriate to the route and individual risk, a plan for distress or an adverse reaction, recovery assessment before departure, and transportation and post-session support planning. Monitoring reduces risk. It does not make ketamine risk-free.

What are the transportation and activity restrictions?

You may not drive yourself home after an experiential session. Arrange for a responsible adult to provide transportation and follow the team’s instructions about accompaniment and post-session support.

Do not drive, operate machinery, make high-stakes decisions, use alcohol or non-prescribed substances, or engage in hazardous activity for at least six hours after a session, until the effects have fully subsided, and until your clinician’s instructions allow it. Follow a longer or route-specific restriction if your clinician gives one.

What are the limits of privacy in a group?

LuminaThera clinicians and staff follow professional and legal confidentiality requirements. Every participant is also asked to protect what others share. The practice cannot guarantee that another participant will keep information confidential.

The team discusses this limit before group work begins and asks each participant to make a clear confidentiality commitment. You control how much personal information you share, within the needs of safe participation.

When should I seek urgent help?

LuminaThera does not provide crisis or emergency services, and website messages and forms are not monitored for urgent needs. In immediate danger or a medical emergency, call 911 or go to the nearest emergency department. In suicidal crisis or emotional distress in the United States, call or text 988.

After a session, seek urgent help for severe or increasing distress, loss of sleep, confusion, unusual beliefs, inability to function, breathing difficulty, loss of consciousness, or thoughts of harming yourself or someone else.

Informed Consent

Questions are part of consent.

This page is a general orientation. Your screening, medication instructions, and informed-consent documents are the sources for decisions about your individual care. You may ask about expected benefits, alternatives, uncertainties, risks, and the option not to proceed at any point.

For details about protected health information, read the Notice of Privacy Practices.

Next Step

Begin with a conversation.

A consult can help clarify whether a LuminaThera pathway may fit. Applying or consulting does not commit you to treatment or guarantee acceptance.